Reserve concomitant prescribing of those medicines in people for whom other treatment method choices are insufficient. Restrict dosages and durations for the minimum amount essential. Monitor carefully for indications of respiratory depression and sedation.
benzhydrocodone/acetaminophen and pentobarbital both increase sedation. Avoid or Use Alternate Drug. Limit use to individuals for whom option procedure options are inadequate
pentobarbital decreases amounts of toremifene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers boost rate of toremifene metabolism, reducing the regular-point out concentration in serum.
pentobarbital will lessen the extent or effect of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Potent or moderate CYP3A4 inducers might enhance level of diazepam elimination; therefore, efficacy of diazepam could be diminished.
pentobarbital will minimize the level or effect of isradipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will reduce the level or result of stiripentol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If struggling to avoid coadministration of stiripentol with powerful CYP3A4 inducers, boost stiripentol dose.
pentobarbital will decrease the level or effect of bazedoxifene/conjugated estrogens 戊巴比妥鈉製作 by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the level or impact of bedaquiline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Stay away from coadministration of bedaquiline with sturdy CYP3A4 inducers due to prospective for diminished therapeutic outcome
pentobarbital will minimize the level or result of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the level or result of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Check people previously on buprenorphine subdermal implant who demand newly-initiated remedy with CYP3A4 inducer for signs and symptoms of withdrawal.
pentobarbital will minimize the level or influence of felodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Contraindicated (one)pentobarbital will lessen the extent or influence of fostemsavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or influence of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
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